OXANDROLONE 10mcg

Oxandrolone 10′ tablets USP are indicated as adjunctive therapy to offset the protein catabolism associated with prolonged administration of corticosteroids, and for the relief of the bone pain frequently accompanying osteoporosis.

Drug interactions:

Anticoagulants: Anabolic steroids may increase sensitivity to oral anticoagulants. Dosage of the anticoagulant may have to be decreased in order to maintain desired prothrombin time. Patients receiving oral anticoagulant therapy require close monitoring,especially when anabolic steroids are started or stopped.

Warfarin: A multidose study of Oxandrolone, given as 5 mg or 10 mg BID in 15 healthy subjects concurrently treated with warfarin, resulted in a mean increase in S-warfarin half-life from 26 to 48 hours and AUC from 4.55 nghr/mL to 12.08 nghr/mL; similar increases in R-warfarin half-life and AUC were also detected.

Microscopic hematuria (9/15) and gingival bleeding (1/15) were also observed.

Overdosage:

No symptoms or signs associated with overdosage have been reported. It is possible that sodium and water retention may occur. The oral LD50 of Oxandrolone10 in mice and dogs is greater than 5,000mg/kg. No specific antidote is known, but gastric lavage may be used.

Precautions:

Concurrent dosing of Oxandrolone10 and warfarin may result in unexpectedly large increases in the INR or prothrombin time (PT).

When Oxandrolone10 is prescribed to patients being treated with warfarin, doses of warfarin may need to be decreased significantly to maintain the desirable IN level and diminish the risk for potentially serious bleeding.

Dosage and adminstration:

Therapy with anabolic steroids is adjunctive to and not a replacement for conventional therapy. The duration of therapy with Oxandrolone10 will depend on the response of the patient and possible appearance of adverse reactions. Therapy should be intermitted. The total daily dose is 50.1 mg per kilogram body weight administered once daily.Adult males:10 -30 mg taken orally per day in 2 to 3 divided doses for 6 to 8weeks, Adult Female;2.5 – 20 mg orally per day in 2 to 3 divided doses for 6 to 8 weeks.

Side effects:

Anabolic steroids may increase sensitivity to oral anticoagulants. Dosage of the anticoagulant may have to be decreased in order to maintain desired prothrombin time. Patients receiving oral anticoagulant therapy require close monitoring,especially when anabolic steroids are started or stopped.

Warfarin: A multidose study of Oxandrolone, given as 5 mg or 10 mg BID in 15 healthy subjects concurrently treated with warfarin, resulted in a mean increase in S-warfarin half-life from 26 to 48 hours and AUC from 4.55 nghr/mL to 12.08 nghr/mL; similar increases in R-warfarin half-life and AUC were also detected.

Abuse In Sports:

Abuse of this product in sports is highly discouraged. Metabolicpharma does not take any responsibility for use of this product for an purpose.

This product should be used under proper medical supervision.

Supplied / storage:

Oxandrolone10 is supplied 50 tablets in a bottle. Tablets should be stored at controlled room temperatures below 30°C and protected from light.

If it has expired or is damaged, return it to your pharmacist for disposal.

Keep out of the reach and sight of children.